MINI REVIEW: the role of homologous recombination in emergence of SARS-CoV-2

Authors

  • Armando Aurélio Mabasso Universidade Eduardo Mondlane (UEM), Faculdade de Ciências, Departamento de Ciências Biológicas
  • Alda Ester Chongo Universidade Eduardo Mondlane (UEM), Faculdade de Ciências, Departamento de Ciências Biológicas
  • Leonel Monteiro Independent Consultant
  • Irina Mendes de Sousa Universidade Eduardo Mondlane (UEM), Faculdade de Ciências, Departamento de Ciências Biológicas
  • Alberto Romão Sineque Universidade Eduardo Mondlane (UEM), Faculdade de Ciências, Departamento de Ciências Biológicas

Keywords:

Homologous recombination, SARS-CoV-2, recombination in RNA viruses

Abstract

During viral recombination, new genetic combinations are generated from the mixing or crossover of two or more nucleic acids from different origins. This process, therefore, requires that more than one virus infects the same cell in order to generate combinations of new viral sequences or chimeric molecules. This process is thought to have an impact in epidemiology, emergence and evolution of RNA viruses. In this mini-review, we highlight the homologous recombination and explain how it might have contributed in the emergence of SARS-CoV-2.

References

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Published

2021-01-08

How to Cite

Mabasso, A. A. ., Chongo, A. E. ., Monteiro, L. ., Sousa, I. M. de ., & Sineque, A. R. . (2021). MINI REVIEW: the role of homologous recombination in emergence of SARS-CoV-2. UEM Scientific Journal: Biomedical Sciences and Public Health Series . Retrieved from http://revistacientifica.uem.mz/revista/index.php/cbsp/article/view/22

Issue

2020: Edição Especial sobre COVID-19

Section

Artigos de revisão

License

Copyright (c) 2020 Revista Científica da UEM: Série Ciências Biomédicas e Saúde Pública

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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